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齐鑫

发布日期:2025-03-06    浏览次数:

【硕士生导师简介】

   

齐鑫


   

出生年月

1987.10

   

博士

   

副教授

   

系主任

   

15201429573

电子邮箱

qixin@usts.edu.cn

【个人简介】

齐鑫,河北昌黎人,2010年获河北农业大学农学学士学位;2016年获中国农业大学理学博士学位。主讲《生物信息学》等课程。主持在研国家自然科学基金面上项目1项,主持完成国家自然科学基金青年项目1项、江苏省高等学校自然科学研究面上项目1项、中国博士后科学基金面上项目1项、江苏省博士后科学基金项目1项。在国内外知名期刊Briefings   in bioinformaticsClinical and translational medicine等发表SCI论文15篇,参与发表论文3篇。

【研究领域】

特定条件下生物基因表达特征和调控机理,包括(1)转录组表达谱数据的系统整合;(2)ceRNA调控网络构建和通路分析;(3)癌症进展过程中基因表达和功能分析;(4)癌症预后风险预测模型的构建与分析。

【项目与获奖】

(一)、承担的科研项目

1、国家自然科学基金面上项目,整合多组学数据解析lncRNA重塑肿瘤免疫微环境促进结直肠癌肝转移的作用机制,2023.1-2026.12,主持,54万,在研

2、国家自然科学基金青年项目,lncRNA介导的ceRNA调控网络在结直肠癌远处转移过程中的功能研究,2020.1-2022.12,主持,22万,结题

3、江苏省高等学校自然科学研究面上项目,基于ceRNA调控网络的结直肠癌发生发展机制研究,2019.7-2021.6,主持,3万,结题

4、第65批中国博士后科学基金面上项目,基于ceRNA调控网络寻找结直肠癌转移相关的生物标志物,2019.9-2021.3,主持8万元,结题

5、江苏省博士后科研资助项目,基于ceRNA调控网络的结直肠癌生物标志物的识别和验证,2018.8-2021.3,主持,2万元,结题

(二)、获奖成果

20249月,苏州科技大学优秀教师

20244月,江苏省“青蓝工程”优秀青年骨干教师

20239月,苏州科技大学“青年教师标兵”(科研类)

20234月,苏州科技大学教案设计比赛,一等奖

2022年度江苏省普通高校本专科优秀毕业论文指导教师

2022年度苏州科技大学本科优秀毕业论文指导教师

2021年度江苏省普通高校本专科优秀毕业论文指导教师

2021年度苏州科技大学本科优秀毕业论文指导教师

202110月,苏州科技大学微课和微课程教学比赛,一等奖

202011月,苏州市自然科学优秀学术论文,三等奖

202012月,苏州科技大学“课程思政”微课教学比赛,二等奖

【论文、论著及授权专利】

1. Xie Shaozhuo, Hou Siyu, Chen Jiajia, Qi   Xin*. Integrative Single-Cell and Bulk RNA Sequencing   Identifies a Macrophage-Related Prognostic Signature for Predicting Prognosis   and Therapy Responses in Colorectal Cancer. International Journal of   Molecular Sciences, 2025, 26(2): 811.

2. Zhao Yuanchun, Xun Dexu, Chen Jiajia, Qi   Xin*. A novel machine learning-based immune prognostic   signature for improving clinical outcomes and guiding therapy in colorectal   cancer: an integrated bioinformatics and experimental study. BMC cancer,   2025, 25(1): 65.

3. Xun Dexu, Li Xue, Huang Lan, Zhao Yuanchun,   Chen Jiajia, Qi Xin*. Machine learning-based analysis   identifies a 13-gene prognostic signature to improve the clinical outcomes of   colorectal cancer. Journal of Gastrointestinal Oncology, 2024, 15(5): 2100.

4. Qi Xin*, Zhao Yuanchun,   Qi Zhuang, Hou Siyu, Chen Jiajia. Machine learning empowering drug discovery:   Applications, opportunities and challenges. Molecules, 2024, 29(4): 903.

5. Hou Siyu, Zhao Yuanchun, Chen Jiajia, Lin   Yuxin, Qi Xin*. Tumor-associated macrophages in colorectal   cancer metastasis: molecular insights and translational perspectives. Journal   of Translational Medicine, 2024, 22(1): 62.

6. Zhao Yuan, Chen Xingqi, Chen Jiajia, Qi   Xin*. Decoding Connectivity Map-based drug repurposing for   oncotherapy. Briefings in bioinformatics, 2023, 24(3): bbad142.

7. Qi Xin, Lin Yuxin, Chen Jiajia,   Shen Bairong*. The landscape of emerging ceRNA crosstalks in   colorectal cancer: Systems biological perspectives and translational   applications. Clinical and translational medicine, 2020, 10(4).

8. Qi Xin#, Lin Yuxin #,   Liu Xingyun, Chen Jiajia and Shen Bairong*. Biomarker discovery   for the carcinogenic heterogeneity between colon and rectal cancers based on   lncRNA-associated ceRNA network analysis. Frontiers in oncology, 2020, 10:   2345.

9. Qi Xin#, Yu Chunjiang#,   Wang Yi, Lin Yuxin, Shen Bairong*. Network vulnerability-based and knowledge-guided identification   of microRNA biomarkers indicating platinum resistance in high-grade serous   ovarian cancer. Clinical and translational medicine, 2019, 8(1): 1-11.

10. Qi Xin#, Lin Yuxin#, Chen Jiajia,   Shen Bairong*.   Decoding competing endogenous RNA networks for cancer biomarker discovery.   Briefings in bioinformatics, 2020, 21(2): 441-457.

11. Qi Xin, Li Shixue, Zhu Yaxi, Zhao   Qian, Zhu Dengyun, Yu Jingjuan*. ZmDof3, a maize endosperm-specific Dof protein gene, regulates   starch, accumulation and aleurone development in maize endosperm. Plant   Molecular Biology, 2016, 93(1): 7-20.

12. Qi Xin #, Xie Shaojun#,   Liu Yuwei#, Yi Fei, Yu Jingjuan*. Genome-wide annotation   of genes and noncoding RNAs of foxtail millet in response to simulated   drought stress by deep sequencing. Plant molecular biology, 2013, 83(4-5):   459-473.

13. Yu Chunjiang#, Qi Xin#,   Lin Yuxin, Li Yin, Shen Bairong*. iODA: An integrated tool for   analysis of cancer pathway consistency from heterogeneous multi-omics data.   Journal of Biomedical Informatics, 2020, 112: 103605.

14. Peng Jing, Qi Xin, Chen Xiyang,   Li Nan, Yu Jingjuan*. ZmDof30 negatively regulates the promoter activity of the   pollen-specific gene Zm908. Frontiers in Plant Science, 2017, 8: 685.

15. Yi Fei#, Xie Shaojun#, Liu Yuwei, Qi Xin, Yu Jingjuan*. Genome-wide characterization of   microRNA in foxtail millet (Setaria italica). BMC plant biology, 2013, 13(1):   212.

16. Liu Chen, Qi Xin, Zhao Qiao, Yu   Jingjuan*.   Characterization and functional analysis of the potato pollen-specific   microtubule-associated protein SBgLR in tobacco. PloS one, 2013, 8(3):   e60543.

 

以上资料更新日期:20252