(一)、承担的科研项目 (1) 国家自然科学基金委员会, 面上项目, 31770903, lncRNA介导的ceRNA调控网络在水稻干旱胁迫应答中的功能研究, 2018.1-2021.12, 60万元, 完成, 主持 (2) 国家自然科学基金委员会, 青年项目, 31400712, 基于microRNA协同调控模块挖掘和验证肾透明细胞癌联合诊断标记, 2015.1-2017.12, 24万元, 完成, 主持 (3) 苏州市科技计划, 农业项目, SNG201905, 氨基酸螯合稀土镧提高水稻抗逆性能的分子机制及应用研究, 2020.1-2022.12, 5万元, 在研, 主持 (4) 江苏省高校自然科学基金,面上项目,13KJB180021,基于microRNA调控网络的新型前列腺癌诊断标记的构建,2014.1-2015.12,完成,主持 (5) 苏州市科技计划, 农业项目, SNG201409, 水稻逆境胁迫应答microRNA标记的筛选及调控机制研究, 2014.7-2017.6, 8万元, 完成, 主持 (二)、获奖成果 2023年6月,苏州科技大学说课竞赛,二等奖 2020年9月,苏州科技大学优秀教学成果奖,二等奖 2020年7月,全国大学生生命科学创新创业大赛,一等奖,指导教师 2019年9月,互联网+创新创业大赛,江苏省三等奖,指导教师 2018年6月,江苏省“青蓝工程”优秀青年骨干教师 2018年9月,苏州科技大学优秀教学成果奖,一等奖 2014年9月,苏州市自然科学优秀学术论文,一等奖 2016年9月,苏州市优秀教育工作者 2008年6月,苏州科技大学青年教师讲课竞赛,一等奖 2018年12月,苏州科技大学青年教师讲课竞赛,一等奖 2013年6月,苏州科技大学微课教学竞赛,一等奖 2013年9月,江苏省微课教学竞赛,三等奖 2014年10月,全国高校微课教学比赛,二等奖 2014年6月,江苏省本科高校青年教师讲课竞赛,二等奖 2014年9月,青年教师标兵 2014年9月,交行奖教金 2015年1月,苏州科技大学优秀青年骨干教师,考核优秀 2016年9月,苏州科技大学优秀教师 2018年1月,苏州科技大学优青培养对象 2018年9月,苏州国际教育园,最佳人气课程奖 |
主要代表性论文: 第一作者: 1. Chen, J, Zhang, Y, Shen, B. Bioinformatics for the Origin and Evolution of Viruses. Adv Exp Med Biol. 2022;1368:53-71. 2. Chen, J., Zhong, Y.,LncRNA TCONS_00021861 is functionally associated with drought tolerance in rice (Oryza sativa) via competing endogenous RNA regulation,BMC Plant Biology,2021.9 3. Chen, J., Zhong, Y., Li, L.:miR‑124 and miR‑203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC), J Transl Med, 2020, 18, 2020 4. Chen, J., Zhong, Y., Li, L.: Integrative analysis reveals drought-responsive microrna-MRNA regulatory modules in Oryza sativa, Basic & Clinical Pharmacology & Toxicology, 2018, 124(1), 2018 5. Chen, J., Zhong, Y., Li, L.: Multiple Regression Analysis Reveals MicroRNA Regulatory Networks in Oryza sativa under Drought Stress, Int J Genomics, 2018: 9395261, 2018 6. Chen, J., Lin, Y., Shen, B.: Informatics for Precision Medicine and Healthcare. Adv Exp Med Biol, 1005: 1, 2017 7. Chen, J., Miao, Z., Xue, B. et al.: Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation. J Cancer, 7: 1842, 2016 8. Chen, J., Shen, B.: RNA Bioinformatics for Precision Medicine. Adv Exp Med Biol, 939: 21, 2016 9. Chen, J., Sun, M., Shen, B.: Deciphering oncogenic drivers: from single genes to integrated pathways. Brief Bioinform, 2014 10. Chen, J., Qian, F., Yan, W. et al.: Translational biomedical informatics in the cloud: present and future. BioMed Research International, 2013: 658925, 2013 11. Chen, J., Shen, B.: Network Biomarkers for Diagnosis and Prognosis of Human Prostate Cancer. In: Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases: Springer Netherlands, pp. 207-220, 2013 12. Chen, J., Wang, Y., Shen, B. et al.: Molecular signature of cancer at gene level or pathway level? Case studies of colorectal cancer and prostate cancer microarray data. Computational and Mathematical Methods in Medicine, 2013: 909525, 2013 13. Chen, J., Zhang, D., Yan, W. et al.: Translational bioinformatics for diagnostic and prognostic prediction of prostate cancer in the next-generation sequencing era. BioMed Research International, 2013: 901578, 2013 14. Chen, J., Zhang, D., Zhang, W. et al.: Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis. Journal of Translational Medicine, 11: 169, 2013 15. Chen, J., Chen, L., Shen, B.: Identification of Network Biomarkers for Cancer Diagnosis. In: Bioinformatics of Human Proteomics. Edited by X. Wang: Springer Netherlands, pp. 257-275, 2012 16. Chen, J., Shen, B.: Computational analysis of amino acid mutation: a proteome wide perspective. Current Proteomics, 6: 228, 2009 17. Chen, J., Wang, Y., Guo, D. et al.: A systems biology perspective on rational design of peptide vaccine against virus infections. Current Topics in Medicinal Chemistry, 12: 1310, 2012 18. Chen, J., Zhang, D., Zhang, W. et al.: An integrative framework for identifying consistent microRNA expression signatures associated with clear cell renal cell carcinoma. Presented at the Systems Biology (ISB), 2012 IEEE 6th International Conference on, Xi'an, China, August 18-20, 2012, 2012 19. Liu, B., Chen, J., Shen, B.: Genome-wide analysis of the transcription factor binding preference of human bi-directional promoters and functional annotation of related gene pairs. BMC Systems Biology, 5: S2, 2011 (共同一作) 通信作者: 1. Zhong, Y., Chen, J.*: Ameliorative effects of Lanthanum(Ⅲ) on Copper(Ⅱ) stressed rice (Oryza sativa) and its molecular mechanism revealed by transcriptome profiling. Plant Physiology and Biochemistry, 2020:152, 2020 2. Gao, Y., Chen, J.*: Informatics for Nutritional Genetics and Genomics. Adv Exp Med Biol, 1005: 143, 2017 3. 20. Shen, Y., Zhang, S., Zhou, J. Chen, J.*: Cohort Research in "Omics" and Preventive Medicine. Adv Exp Med Biol, 1005: 193, 2017 4. Yan, W., Wang, S., Sun, Z., Chen, W., Chen, J.*: Identification of microRNAs as potential biomarker for gastric cancer by system biological analysis. Biomed Res Int, 2014: 901428, 2014 代表性授权专利: 1. 发明专利 2021.06授权 提高砷胁迫水稻耐受性的microRNA基因及其应用 发明专利 201810191587.7第一作者 |